Line 443 deals with the 5. Nc3 line in the Kan Variation of the Sicilian Defense, though reactions with 5… Nc6 and 5… Qc7 belong elsewhere. There are two main options for Black: quite popular 5… b5, and the more solid 5… d6.
The first of the two lost a lot of its popularity in recent years, mainly because 6. Bd3 Qb6 7. Nf3 proved very dangerous, e. g. in a theoretically important game A. Grischuk – P. Svidler, Khanty-Mansiysk 2011.
[Diagram: White to Move] A typical reaction from White soon gives him a decisive advantage!
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